On November 18, 2025, Proofpoint, Inc. launched its Proofpoint Satori™ Emerging Threats Intelligence Agent directly into Microsoft Security Copilot — a move that could reshape how enterprises prioritize patching before attackers strike. The integration, announced from Sunnyvale, California, gives security teams real-time visibility into which vulnerabilities are actually being exploited in the wild, not just listed on paper. For the first time, defenders can ask Security Copilot a simple question — "Is CVE-2025-12345 being actively targeted?" — and get an answer backed by live data from Proofpoint’s global sensor network, CISA’s Known Exploited Vulnerabilities list, and FIRST’s EPSS scoring system. No more guessing. No more delays.
Why This Matters More Than Ever
The average organization now faces over 1,200 newly disclosed vulnerabilities each month. But only about 12% of them are ever exploited — yet security teams still waste weeks chasing every alert. The twist? Attackers aren’t waiting. According to Proofpoint’s internal telemetry, 73% of breaches in 2025 started with a known, unpatched vulnerability that had been flagged for over 30 days. That’s not negligence — it’s noise. And now, Proofpoint, Inc. is cutting through it.The Satori agent doesn’t just report data — it understands context. It knows that a vulnerability rated "critical" by NVD might be irrelevant if no active campaigns are targeting it. Meanwhile, a "moderate" flaw with spikes in exploitation across financial institutions? That’s the one you patch first. It’s like having a veteran SOC analyst who’s seen every attack pattern since 2018, working 24/7 without coffee breaks.
The Satori Ecosystem: More Than One Agent
This isn’t a one-off tool. Proofpoint’s Satori platform is a suite of AI-powered assistants built to automate the grunt work that burns out security teams. The Proofpoint Satori™ DLP Triage Agent cuts through 90% of false positives in data loss prevention alerts. The Proofpoint Satori™ Phishing Simulation Agent automatically designs targeted phishing drills based on real campaigns observed in the wild. And the Proofpoint Satori™ Abuse Mailbox Agent processes thousands of "Needs Manual Review" emails in seconds — a task that used to take teams days.What ties them together? Proofpoint Satori™ MCP Access, which uses the Model Context Protocol to let these agents talk to each other — and to tools like Microsoft Copilot and CrowdStrike Charlotte. Think of it as a secure, AI-powered Slack channel for your entire security stack.
Attackers Are Targeting AI Itself
Here’s the chilling part: bad actors aren’t just exploiting systems — they’re exploiting the assistants meant to protect them. Proofpoint researchers have documented malicious emails embedding prompt injections designed to trick Microsoft Copilot and Google Gemini into leaking credentials or executing unauthorized commands. One campaign in October 2025 fooled a financial services firm’s AI assistant into sending internal threat reports to a hacker-controlled email. These aren’t theoretical threats. They’re happening now.That’s why Proofpoint’s new Proofpoint Prime Threat Protection solution includes AI exploit detection for email — rolling out in Q4 2025. It doesn’t just scan for malware. It looks for linguistic patterns that signal prompt injection, even if the message looks clean. "We’re no longer defending just the inbox," said CEO Sumit Dhawan at Proofpoint Protect 2025. "We’re defending the AI that’s now sitting at every analyst’s desk."
What’s Next? The AI Security Arms Race
Proofpoint isn’t stopping here. The Proofpoint Secure Agent Gateway and additional Satori Agents will enter phased availability in 2026, giving enterprises control over which AI tools can interact with which systems. Meanwhile, Proofpoint Data Security Complete — launched in Q3 2025 — is adding new AI-driven classification and encryption features over the next two quarters.What’s clear? The future of cybersecurity isn’t just faster firewalls or bigger data lakes. It’s AI agents that work together, learn from each other, and protect the humans who rely on them. And right now, Proofpoint, Inc. is leading the charge.
Frequently Asked Questions
How does the Proofpoint Satori Agent improve vulnerability prioritization over traditional tools?
Traditional vulnerability scanners rely on CVSS scores, which often overstate risk. The Satori Agent uses real-world exploitation data from Proofpoint’s global sensors and CISA’s KEV catalog to show which flaws are actually being used in attacks. This reduces alert fatigue by 60–70% and lets teams focus on the 5–10% of vulnerabilities that matter most.
Can the Satori Agent be used without Microsoft Security Copilot?
No — the Emerging Threats Intelligence Agent is designed specifically to integrate with Microsoft Security Copilot via the Microsoft Security Store. However, other Satori Agents like the DLP Triage and Abuse Mailbox tools operate independently on Proofpoint’s platform and can connect to other SIEMs and SOAR systems through MCP Access.
What’s the difference between Proofpoint Satori and Proofpoint Prime Threat Protection?
Satori refers to the suite of AI agents that automate security tasks like triage and phishing simulation. Prime Threat Protection is the broader defensive layer that includes AI-powered email exploit detection, designed to block malicious prompts targeting AI assistants before they reach inboxes. Satori enhances response; Prime blocks the initial attack.
When will AI exploit detection for email be available?
Proofpoint plans to roll out AI-powered email exploit detection in Q4 2025 as part of its Prime Threat Protection solution. This feature will analyze email content for linguistic patterns associated with prompt injection attacks — a growing threat targeting AI assistants like Copilot and Gemini.
How does MCP Access improve security operations?
MCP Access lets Satori Agents securely share context — like threat alerts, user behavior, and email metadata — with third-party tools such as CrowdStrike and Microsoft Copilot. This eliminates data silos, reduces duplicate investigations, and enables coordinated responses across tools that previously operated in isolation.
Is this technology only for large enterprises?
While initially targeted at large organizations with complex security stacks, Proofpoint plans to offer scaled versions of Satori Agents to mid-market customers in 2026. The goal is to make AI-powered threat prioritization accessible to any organization managing more than 500 endpoints — not just Fortune 500 firms.